Analytical Data
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Gene name
PAP
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简介
PAP proteins play a dual regulatory role in cell growth, exhibiting different effects depending on the specific growth factors involved. In fibroblasts, it exerts a positive regulatory effect by enhancing PDGFA-stimulated cell growth. PAP Protein, Human (His) is the recombinant human-derived PAP protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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Alternative Names
28 kDa Heat- and Acid-Stable Phosphoprotein; PDGF-Associated Protein; PAP; PDGFA-Associated Protein 1; PAP1; PDAP1; HASPP28
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Species
Human
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q13442
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Expression Region
M1-K181
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AA Sequence
MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK
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Protein Length
Full Length
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Molecular Weight
30.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on PAP (Pseudomonas aeruginosa Protein) recombinant proteins has gained significant attention due to their potential applications in biotechnology and medicine. Pseudomonas aeruginosa, a versatile and opportunistic pathogen, poses severe health risks, particularly in immunocompromised individuals, due to its ability to develop resistance to multiple antibiotics. Understanding the structure and function of PAP and its related proteins can provide insights into the mechanisms of bacterial virulence, helping to identify novel therapeutic targets. Recombinant technology enables the production of these proteins in larger quantities and with higher purity, facilitating the development of diagnostic tools and vaccines. Moreover, studying the immune response elicited by PAP recombinant proteins could lead to innovative strategies for infection control and prevention. The exploration of PAP and its derivatives is critical not only for understanding Pseudomonas aeruginosa pathogenicity but also for advancing the field of infectious diseases and improving patient outcomes.











