Analytical Data
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Gene name
NUP210
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简介
NUP210 Protein, a nucleoporin, crucially contributes to nuclear pore assembly, spacing, and structural integrity, ensuring proper nuclear pore function for molecular transport between the nucleus and cytoplasm. NUP210 forms dimers and potentially higher-order oligomers, highlighting its intricate role in nuclear pore architecture. NUP210 Protein, Human (sf9, GST) is the recombinant human-derived NUP210 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
- Application
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Alternative Names
Nucleoporin 210; POM 210; Nuclear pore membrane glycoprotein 210
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Species
Human
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Source
Baculovirus
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Tag
N-GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TEM1-1
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Expression Region
L1837-H1887
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NUP210, a member of the nuclear pore complex (NPC) family, plays a crucial role in nucleocytoplasmic transport, which is essential for cellular function and gene regulation. Due to its significant involvement in various cellular processes, including RNA transport and protein synthesis, NUP210 has gained attention in the field of molecular biology and biomedicine. Research has indicated that alterations in NUP210 expression or function may be linked to several diseases, including cancer and viral infections, where the manipulation of nucleocytoplasmic transport is a common strategy employed by pathogens. The recombinant production of NUP210 protein allows for advanced studies regarding its structure, function, and interaction with other cellular components, facilitating a deeper understanding of its role in health and disease. Moreover, the availability of recombinant NUP210 protein paves the way for developing therapeutic strategies that target its pathways, potentially leading to innovative treatments for diseases associated with dysfunctional nucleocytoplasmic transport. Thus, the exploration of NUP210 as a recombinant protein is pivotal for both basic research and therapeutic advancements, highlighting its relevance in the ongoing quest to understand complex cellular mechanisms.
