Analytical Data
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Gene name
West Nile Virus NS1
- Application
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Alternative Names
West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein
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Species
Virus
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Source
HEK293
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
YP_001527881.1
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Expression Region
D1-A352
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
West Nile Virus (WNV) is a mosquito-borne flavivirus responsible for significant neurological disease in humans and various other vertebrates. Among the proteins encoded by the WNV genome, the non-structural protein 1 (NS1) plays a critical role in the virus's pathogenesis and immune evasion, making it a target of interest for both research and vaccine development. NS1 is involved in the viral life cycle, modulating the host's immune response, and is secreted in either soluble or membrane-associated forms. Studies have shown that NS1 can elicit an immune response, indicating its potential as a biomarker for infection and a candidate for vaccine formulation. Furthermore, the ability to produce recombinant NS1 protein allows researchers to investigate its biological functions, structure, and interactions with the immune system. Understanding the characteristics of NS1 is essential for developing effective diagnostics and therapeutics against WNV, as well as for elucidating the mechanisms by which this virus alters host immune responses. Given the global spread of WNV and its public health implications, prioritizing research on NS1 and its recombinant forms is crucial for advancing our knowledge and improving strategies for disease prevention and control.
