Analytical Data
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Gene name
TIM-16
- Application
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Alternative Names
Mitochondria-associated granulocyte macrophage CSF-signaling moleculePresequence translocated-associated motor subunit PAM16
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y3D7
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Expression Region
1-125aa
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Molecular Weight
40.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TIM-16, a member of the mitochondrial chaperone family, has garnered significant attention in recent years due to its critical role in maintaining mitochondrial function and cellular homeostasis. Mitochondria, often referred to as the powerhouses of the cell, are essential for energy production, and their dysfunction is linked to various diseases, including neurodegenerative disorders and metabolic syndromes. The TIM-16 protein is involved in the translocation of proteins into the mitochondria, facilitating proper mitochondrial biogenesis and dynamics. Research has shown that TIM-16 interacts with other chaperones and proteins in the mitochondrial import machinery, highlighting its importance in protein folding and quality control within this organelle. Understanding the molecular mechanisms governing TIM-16's function could provide insights into the pathophysiology of mitochondrial diseases and reveal potential therapeutic targets. Furthermore, the study of TIM-16 may illuminate broader aspects of cellular stress responses and metabolic regulation, as mitochondria play a central role in these processes. Given the increasing incidence of mitochondrial-related diseases, advancing our understanding of TIM-16 and its biological significance is of paramount importance for developing effective interventions and treatments.
