Analytical Data
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Gene name
SPESP1
- Application
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Alternative Names
Sperm Equatorial Segment Protein 1; ESP; Equatorial Segment Protein; SP-ESP; Glycosylated 38 kDa Sperm Protein C-7/8; SPESP1
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Species
Human
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Source
HEK293
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Tag
C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UW49
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Expression Region
Y20-Y350
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AA Sequence
YPSITVTPDEEQNLNHYIQVLENLVRSVPSGEPGREKKSNSPKHVYSIASKGSKFKELVTHGDASTENDVLTNPISEETTTFPTGGFTPEIGKKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPAAKQTEAPRMLPVVTESSTSPYVTSYKSPVTTLDKSTGIGISTESEDVPQLSGETAIEKPEEFGKHPESWNNDDILKKILDINSQVQQALLSDTSNPAYREDIEASKDHLKRSLALAAAAEHKLKTMYKSQLLPVGRTSNKIDDIETVINMLCNSRSKLYEYLDIKCVPPEMREKAATVFNTLKNMCRSRRVTALLKVY
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Protein Length
Full Length of Mature Protein
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Molecular Weight
58 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPESP1, or Sperm-Egg-Specific Protein 1, is a crucial protein involved in reproduction, particularly in processes related to gamete interaction and fertilization. Research into SPESP1 has gained significance due to its potential implications in fertility, as it plays a pivotal role in the binding and fusion of sperm and egg cells. Understanding the structure and function of SPESP1 can provide valuable insights into reproductive biology and the mechanisms underlying fertilization. Moreover, alterations in SPESP1 expression or function could contribute to infertility issues, making it a target for therapeutic interventions. Advances in recombinant protein technologies have enabled the production of SPESP1 for experimental studies, facilitating investigations into its role in reproductive processes. Continued research on SPESP1 not only enhances our comprehension of gamete biology but also holds promise for developing novel reproductive therapies and improving assisted reproductive technologies.
