Analytical Data
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基因名
CLEC4A3
- Application
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别名
Dendritic cell inhibitory receptor 3; RCG30018; Dcir3
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种属
Rat
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表达系统
HEK293
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标签
N-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5YIS0
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表达区间
L68-L237
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蛋白长度
Cytoplasmic Domain
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分子量
58 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CLEC4A3, a member of the C-type lectin receptor family, has garnered significant attention in recent years due to its potential role in immune response and pathogen recognition. This receptor is primarily expressed on dendritic cells and macrophages, where it participates in mediating the innate immune response. Research indicates that CLEC4A3 can recognize specific carbohydrate structures on pathogens, leading to the activation of immune signaling pathways. Studies suggest that this receptor may have implications in various diseases, including infections, autoimmune disorders, and cancer. Understanding the structure and function of CLEC4A3 is crucial for exploring its therapeutic potential and developing novel immunomodulatory strategies. The generation of recombinant CLEC4A3 proteins facilitates detailed studies on its ligand specificity, signaling mechanisms, and interactions with other immune components, paving the way for advancements in immunotherapy and vaccine design. As researchers delve deeper into CLEC4A3's biological significance, the insights gained could broaden our understanding of immune regulation and enhance the development of targeted treatments for immune-related conditions.
