Analytical Data
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Gene name
Carboxylesterase 1C
- Application
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Alternative Names
PES-N, Ces1c; Es1; Liver carboxylesterase N; Lung surfactant convertase
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P23953
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Expression Region
Gly31~Arg286
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Carboxylesterase 1C (CES1C) is an important enzyme belonging to the carboxylesterase family, which plays a critical role in the hydrolysis of various ester compounds, including drugs and environmental contaminants. Its ability to metabolize a wide range of substrates makes CES1C significant in pharmacokinetics and toxicology. The study of CES1C is particularly relevant in the context of drug metabolism, as variations in this enzyme's activity can influence the efficacy and safety of therapeutic agents. Moreover, CES1C has potential implications in understanding resistance to certain drugs and the metabolic activation of prodrugs. Research into recombinant CES1C offers insights into its structure-function relationships, enabling a more detailed examination of its catalytic mechanisms and substrate specificity. Furthermore, the production of recombinant CES1C can facilitate high-throughput screening of potential drug candidates and the investigation of drug-drug interactions. Understanding this enzyme's function at a molecular level could lead to improved drug design and personalized medicine approaches, highlighting its significance in biomedical research.
