Recombinant Human CD131 Protein(HEK293), His

CD131

The CD131 protein is a cell surface receptor that plays a critical role in the immune response and controls the generation and differentiation of hematopoietic progenitor cells. CD131 Protein, Human (HEK293, His) is the recombinant human-derived CD131 protein, expressed by HEK293 , with C-10*His labeled tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Measured by its binding ability in a functional ELISA. Recombinant Human CD131 binds Recombinant Human GM-CSF (5 μg/mL, 100 μL/well) in the presence of Recombinant Human GM-CSF R alpha. The ED50 for this effect is <120 ng/mL. Measured by its binding ability in a functional ELISA. Recombinant Human CD131 binds Recombinant Human GM-CSF (5 μg/mL, 100 μL/well) in the presence of Recombinant Human GM-CSF R alpha. The ED50 for this effect is 96.35 ng/mL.

Cytokine receptor common subunit beta; CDw131; CD131; CSF2RB; IL3RB; IL5RB

Human

HEK293

C-10*His

Greater than 90% as determined by SDS-PAGE.

P32927-1

W17-W443

Extracellular Domain

55-70 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.