Analytical Data
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Gene name
BTN1A1
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简介
BTN1A1 Protein is implicated in milk-fat droplet secretion and may serve as a membrane-associated receptor in lactation processes. Additionally, it exhibits immune-regulatory functions, inhibiting T-cell proliferation and modulating cytokine secretion. BTN1A1's association with xanthine dehydrogenase/oxidase suggests diverse cellular functions, inviting further exploration into its role in various biological pathways. BTN1A1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived BTN1A1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.
- Application
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Alternative Names
Butyrophilin Subfamily 1 Member A1; BT; BTN
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Species
Human
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Source
HEK293
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Tag
C-Avi;C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13410
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Expression Region
A27-R242
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AA Sequence
SAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPR
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Protein Length
Extracellular Domain
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Molecular Weight
35-40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BTN1A1, or butyrophilin subfamily 1 member A1, is a significant protein implicated in various biological processes, including immune response and cell signaling. It belongs to the butyrophilin family, which is known for its role in modulating T cell activity and influencing the proliferation and differentiation of immune cells. BTN1A1 has garnered attention due to its involvement in the development of certain diseases, particularly in cancer, autoimmune disorders, and infections. Researchers are increasingly interested in recombinant BTN1A1 protein for its potential therapeutic applications and as a tool for understanding its biological functions. The production of this recombinant protein allows for detailed study of its structure, function, and interactions with other biomolecules, which can elucidate its role in immunological responses and disease mechanisms. Moreover, BTN1A1's expression levels and functional variations among different populations present further avenues for investigation, making it a focus of current biomedical research aimed at developing targeted therapies and improving overall human health.
