Recombinant Rhesus Macaque CD1C-B2M Heterodimer Protein(HEK293), His

CD1C-B2M Heterodimer

CD1C belongs to Group 1 of the transmembrane glycoprotein CD1 family. CD1C protein, as a key antigen-presenting molecule, has shown the ability to bind both self and non-self lipid and glycolipid antigens, mediating host defense against tuberculosis. CD1C is associated with breast cancer prognosis and immune invasion. CD1C-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His) is a recombinant protein dimer complex containing Rhesus Macaque-derived CD1C-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. CD1C-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His), has molecular weight of ~44.7 (33.1+ 11.6) KDa.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Measured by its binding ability in a functional ELISA. Immobilized Rhesus Macaque CD1C-B2M Heterodimer, at 2μg/mL (100μL/well) can bind Anti-CD1C antibody. The ED50 for this effect is 0.1125 μg/mL. Measured by its binding ability in a functional ELISA. Immobilized Rhesus Macaque CD1C-B2M Heterodimer, at 2 μg/mL (100 μL/well) can bind Anti-CD1C antibody. The ED50 for this effect is 0.1125 μg/mL.

T-cell surface glycoprotein CD1c; CD1C; Beta-2-microglobulin; B2M

Rhesus Macaque

HEK293

C-6*His

Greater than 90% as determined by SDS-PAGE.

NP_001139005 (Q21-F298)&NP_001040602

NP_001139005 (Q21-F298)&NP_001040602 (I21-M119)

38 & 12 kDa.

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.