Analytical Data
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基因名
CD300c
- Application
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别名
(CLM-6)(CD300 antigen-like family member C)(CD antigen CD300c)
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种属
Mouse
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A2A7V7
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表达区间
22-188aa
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分子量
45.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD300c is a member of the CD300 family of immunoregulatory receptors, which play essential roles in modulating immune responses. It is predominantly expressed on myeloid cells, including dendritic cells, macrophages, and neutrophils, and is involved in the regulation of inflammation and immune tolerance. Research has shown that CD300c can inhibit cell activation and cytokine production when engaged with specific ligands, thus influencing the outcome of immune responses. The therapeutic potential of targeting CD300c has garnered interest in the field of immunology, particularly in developing strategies for autoimmune diseases, cancer immunotherapy, and infectious diseases. Moreover, understanding the molecular pathways associated with CD300c activity may unveil novel mechanisms for immune regulation. Recombining CD300c as a protein allows for in-depth analysis of its structure-function relationship, interactions with ligands, and its downstream signaling pathways. These studies contribute to the broader understanding of immune modulation and offer promising avenues for innovative therapeutic interventions.
