Analytical Data
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基因名
CCR2
- Application
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别名
(C-C CKR-2)(CC-CKR-2)(CCR-2)(CCR2)(JE/FIC receptor)(MCP-1 receptor)(CD antigen CD192)
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51683
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表达区间
1-55aa
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分子量
13.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCR2 (C-C chemokine receptor type 2) is a vital chemokine receptor involved in the immune response, specifically in the migration of monocytes and other immune cells to sites of inflammation. Its role is critical in various pathological conditions, including atherosclerosis, autoimmune diseases, and cancer. Research targeting CCR2 has gained prominence due to its potential as a therapeutic target, particularly in modulating immune responses and alleviating chronic inflammatory disorders. The study of CCR2 recombinant proteins is crucial in understanding its structure-function relationships, signaling mechanisms, and interactions with ligands. These recombinant proteins can be utilized in various applications, including vaccine development, receptor binding studies, and drug screening assays. Scientists have been focused on producing and characterizing CCR2 recombinant proteins to further investigate their biological functions and therapeutic implications. Understanding CCR2 dynamics through its recombinant forms has the potential to unveil novel strategies for the treatment of diseases associated with immune dysregulation. Additionally, exploring CCR2's role could lead to breakthroughs in precision medicine, offering possibilities for targeted therapies that minimize side effects while enhancing treatment efficacy. The ongoing research into CCR2 and its recombinant proteins represents a promising avenue for advancing our knowledge of immune regulation and developing innovative therapeutic approaches.
