Analytical Data
-
基因名
CCR2b
-
简介
CCR2b Protein-VLP, Human (Biotinylated, HEK293) is available in solution form, no concentration information, recommended only for SPR analysis. HY-P77589 can be used in animal immunization, ELISA, PK assay. If VLP control is required, it is recommended HY-P702775. May have binding signals with Anti-His antibodies.
- Application
-
别名
C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2
-
种属
Human
-
表达系统
HEK293
-
标签
Tag Free
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P41597-2
-
表达区间
M1-L360
-
蛋白长度
Full Length of Isoform-2
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCR2b, a chemokine receptor, is primarily involved in the immune response by mediating the migration of monocytes and other immune cells to sites of inflammation. It is a critical component in various pathological conditions, including autoimmune diseases, chronic inflammatory disorders, and cancer. The significance of CCR2b in these processes has made it a relevant target for therapeutic intervention. Research has demonstrated that CCR2b not only influences the accumulation of immune cells but also plays a role in modulating the inflammatory microenvironment, impacting disease progression. Additionally, recent studies have highlighted the potential of CCR2b as a biomarker for disease severity and treatment response. The recombinant expression of CCR2b protein allows for more extensive investigations into its functional mechanisms and interactions with ligands, contributing to the development of CCR2b-targeted drugs. Understanding the structure-function relationship of CCR2b through recombinant protein studies could lead to novel therapeutic strategies aimed at regulating immune responses and controlling inflammation, thus improving clinical outcomes in patients with conditions associated with aberrant CCR2b activity.
