Analytical Data
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Gene name
FSD1
- Application
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Alternative Names
Fibronectin type 3 and SPRY (spla; ryanodine) domain containing (with coiled-coil motif) 1; Fibronectin type 3 and SPRY domain containing 1; Fibronectin type III and SPRY domain containing 1; Fibronectin type III and SPRY domain-containing protein 1; Fibronectin type III and SPRY domains containing protein 1; FSD1; FSD1_HUMAN; GLFND; MGC3213; MGC58341
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BTV5
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Expression Region
1-309aa
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AA Sequence
MPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT
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Molecular Weight
59.73 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FSD1 (Ferritin-like protein 1) is a crucial enzyme involved in iron metabolism and homeostasis within cells. Its role has become increasingly significant in understanding various biological processes, including cellular response to oxidative stress and the regulation of iron levels in the body. Research into FSD1 has grown due to its potential implications in diseases related to iron dysregulation, such as neurodegenerative disorders, anemia, and metabolic syndromes. Studies have shown that FSD1 interacts with other proteins and cellular pathways, making it a key player in managing cellular iron distribution and storage. Furthermore, its expression patterns and activity can vary under different physiological conditions, prompting scientists to investigate its regulatory mechanisms and functional implications. Recombination techniques have enabled the production of FSD1 recombinant proteins, which are essential for exploring its structure-function relationships in detail. By elucidating the molecular mechanisms behind FSD1, researchers aim to uncover new therapeutic targets for related diseases, thereby contributing to advances in biomedical interventions and improving our understanding of iron metabolism in health and disease.
