Analytical Data
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Gene name
TSPAN5
- Application
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Alternative Names
TSPAN5; TM4SF9; Tetraspanin-5; Tspan-5; Tetraspan NET-4; Transmembrane 4 superfamily member 9
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62079
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Expression Region
1-268 aa
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AA Sequence
MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW
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Molecular Weight
55.22 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TSPAN5, a member of the tetraspanin superfamily, has garnered attention in recent years due to its potential roles in various physiological and pathological processes, including cell adhesion, proliferation, and immune response modulation. Tetraspanins are known to organize membrane microdomains and facilitate interactions between different cell surface proteins, leading to significant implications in cancer biology and infectious diseases. Research has indicated that TSPAN5 may be involved in the regulation of cellular pathways critical for tumor growth and progression, making it a potential biomarker and therapeutic target in cancer treatment. Furthermore, studies have suggested that TSPAN5 is implicated in the immune system, influencing the activation and differentiation of immune cells, particularly in the context of autoimmune diseases. This has spurred interest in the development of recombinant TSPAN5 proteins for functional assays and therapeutic applications. The production and characterization of TSPAN5 recombinant proteins are crucial for elucidating its biological functions and the mechanisms underlying its role in various diseases, thus advancing our understanding of its potential applications in clinical settings.
