Analytical Data
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基因名
CALB
- Application
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别名
CALB；CNA2；CNB；Calcineurin subunit B type 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22676
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表达区间
1-271aa
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氨基酸序列
MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSSA EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD RSGYIDEHEL DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEAGKLYRKD LEIVLCSEPP M
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CALB (calbindin) is a calcium-binding protein that plays a crucial role in calcium homeostasis and signaling in various biological processes. Research into CALB recombinant proteins has gained momentum due to their potential applications in neuroscience, cell biology, and therapeutic development. The ability of CALB to bind calcium ions not only helps in regulating intracellular calcium levels but also influences neuronal excitability and synaptic plasticity, making it a key focus in the study of neural functions and neurodegenerative diseases. Recombinant CALB is often produced using advanced molecular biology techniques to facilitate detailed investigations into its structure-function relationships, as well as its interactions with other proteins and ions. This research is particularly relevant in understanding calcium-related disorders, such as Alzheimer's disease, where impaired calcium signaling is implicated. Furthermore, the engineering of CALB can lead to novel biomaterials and drug delivery systems, enhancing its biomedical relevance. Ongoing studies aim to elucidate the physiological roles of CALB and develop innovative therapeutic strategies targeting calcium dysregulation in various diseases, highlighting the importance of CALB recombinant proteins in advancing our understanding of calcium biology and its implications for human health.
