Analytical Data
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基因名
SSX2IP
- Application
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别名
ADIP; ADIP_HUMAN; Afadin and alpha actinin binding Protein ; Afadin DIL domain interacting Protein; Afadin DIL domain-interacting Protein; Afadin- and alpha-actinin-binding Protein; FLJ10848; KIAA0923; MGC75026; OTTHUMP00000011574; SSX 2 interacting Protein; SSX2 interacting Protein; SSX2-interacting Protein; SSX2IP; Synovial sarcoma X breakpoint 2 interacting Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2D8
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表达区间
1-614 aa
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氨基酸序列
MGDWMTVTDP GLSSESKTIS QYTSETKMSP SSLYSQQVLC SSIPLSKNVH SFFSAFCTED NIEQSISYLD QELTTFGFPS LYEESKGKET KRELNIVAVL NCMNELLVLQ RKNLLAQENV ETQNLKLGSD MDHLQSCYSK LKEQLETSRR EMIGLQERDR QLQCKNRNLH QLLKNEKDEV QKLQNIIASR ATQYNHDMKR KEREYNKLKE RLHQLVMNKK DKKIAMDILN YVGRADGKRG SWRTGKTEAR NEDEMYKILL NDYEYRQKQI LMENAELKKV LQQMKKEMIS LLSPQKKKPR ERVDDSTGTV ISDVEEDAGE LSRESMWDLS CETVREQLTN SIRKQWRILK SHVEKLDNQV SKVHLEGFND EDVISRQDHE QETEKLELEI QQCKEMIKTQ QQLLQQQLAT AYDDDTTSLL RDCYLLEEKE RLKEEWSLFK EQKKNFERER RSFTEAAIRL GLERKAFEEE RASWLKQQFL NMTTFDHQNS ENVKLFSAFS GSSDWDNLIV HSRQPQKKPH SVSNGSPVCM SKLTKSLPAS PSTSDFCQTR SCISEHSSIN VLNITAEEIK PNQVGGECTN QKWSVASRPG SQEGCYSGCS LSYTNSHVEK DDLP
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分子量
71.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SSX2IP, or SSX2-interacting protein, is a member of the cancer/testis (CT) antigen family known for its expression in various tumors, including melanoma and non-small cell lung cancer, while being predominantly absent in normal tissues. This unique expression pattern makes SSX2IP a potential target for cancer immunotherapy, as it might elicit a robust immune response in tumor-bearing patients. Recent studies have highlighted the role of SSX2IP in regulating cellular processes such as cell cycle progression and apoptosis, suggesting its involvement in tumorigenesis. Furthermore, SSX2IP has been shown to interact with key proteins involved in signal transduction pathways, indicating its potential as a regulatory factor in oncogenic signaling. The investigation of SSX2IP recombinant protein is crucial for understanding its functional properties, cellular interactions, and implications in cancer biology. By generating SSX2IP as a recombinant protein, researchers can study its structure-function relationship, develop assays to explore its interactions with various binding partners, and assess its potential as a biomarker for cancer diagnosis and prognosis. Additionally, the recombinant protein can be utilized in developing therapeutic vaccines aimed at eliciting an immune response against tumors expressing SSX2IP, paving the way for innovative treatment strategies. Overall, the study of SSX2IP recombinant protein holds promise for advancing our understanding of tumor biology and enhancing therapeutic options for cancer patients.
