Analytical Data
-
Gene name
SPSB4
- Application
-
Alternative Names
SPSB4; SSB4; SPRY domain-containing SOCS box protein 4; SSB-4
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96A44
-
Expression Region
1-273aa
-
AA Sequence
MGQKLSGSLK SVEVREPALR PAKRELRGAE PGRPARLDQL LDMPAAGLAV QLRHAWNPED RSLNVFVKDD DRLTFHRHPV AQSTDGIRGK VGHARGLHAW QINWPARQRG THAVVGVATA RAPLHSVGYT ALVGSDAESW GWDLGRSRLY HDGKNQPGVA YPAFLGPDEA FALPDSLLVV LDMDEGTLSF IVDGQYLGVA FRGLKGKKLY PVVSAVWGHC EVTMRYINGL DPEPLPLMDL CRRSIRSALG RQRLQDISSL PLPQSLKNYL QYQ
-
Molecular Weight
30.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPSB4, or spermatogenesis-associated protein 4, is a member of the SPSB family of proteins, which are known to play crucial roles in various biological processes, including gene regulation, cell signaling, and immune responses. The interest in SPSB4 has grown due to its potential implication in reproductive health and its involvement in the regulation of proteasome-mediated degradation of cellular proteins. Research has indicated that SPSB4 may function as an important adapter in the ubiquitin-proteasome system, influencing processes such as cell differentiation and apoptosis. Furthermore, studies have suggested that SPSB4 could be linked to certain diseases, including cancer and autoimmune disorders, highlighting its relevance in pathological conditions. Understanding the structure and function of SPSB4 is essential for elucidating its role in normal physiology and disease states. Recent advances in recombinant protein technology have allowed researchers to produce and study SPSB4 in detail, enabling the exploration of its biochemical properties, interaction partners, and regulatory mechanisms. Given the complex role of SPSB4 in cellular processes, ongoing research aims to unravel its functions and therapeutic potential, particularly in the context of male fertility and related health issues.
