Analytical Data
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Gene name
DKFZp547C195
- Application
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Alternative Names
DKFZp547C195; RING finger protein 214; RN214_HUMAN; RNF214
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8ND24
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Expression Region
2-703aa
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AA Sequence
AASEVAGVV ANAPSPPESS SLCASKSDEG LPDGLSTKDS AQKQKNSPLL SVSSQTITKE NNRNVHLEHS EQNPGSSAGD TSAAHQVVLG ENLIATALCL SGSGSQSDLK DVASTAGEEG DTSLRESLHP VTRSLKAGCH TKQLASRNCS EEKSPQTSIL KEGNRDTSLD FRPVVSPANG VEGVRVDQDD DQDSSSLKLS QNIAVQTDFK TADSEVNTDQ DIEKNLDKMM TERTLLKERY QEVLDKQRQV ENQLQVQLKQ LQQRREEEMK NHQEILKAIQ DVTIKREETK KKIEKEKKEF LQKEQDLKAE IEKLCEKGRR EVWEMELDRL KNQDGEINRN IMEETERAWK AEILSLESRK ELLVLKLEEA EKEAELHLTY LKSTPPTLET VRSKQEWETR LNGVRIMKKN VRDQFNSHIQ LVRNGAKLSS LPQIPTPTLP PPPSETDFML QVFQPSPSLA PRMPFSIGQV TMPMVMPSAD PRSLSFPILN PALSQPSQPS SPLPGSHGRN SPGLGSLVSP HGPHMPPAAS IPPPPGLGGV KASAETPRPQ PVDKLEKILE KLLTRFPQCN KAQMTNILQQ IKTARTTMAG LTMEELIQLV AARLAEHERV AASTQPLGRI RALFPAPLAQ ISTPMFLPSA QVSYPGRSSH APATCKLCLM CQKLVQPSEL HPMACTHVLH KECIKFWAQT NTNDTCPFCP TLK
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Molecular Weight
77.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DKFZp547C195 is a recombinant protein that has garnered attention in the field of cancer research, particularly in the context of understanding tumor biology and developing novel therapeutic strategies. This protein is a variant of a larger family of proteins involved in crucial cellular processes, including proliferation, differentiation, and apoptosis. Its association with various cancers has sparked interest in elucidating its specific role in tumorigenesis. Previous studies have indicated that DKFZp547C195 may act as a biomarker for specific cancer types, providing insights into tumor progression and potential responses to treatment. Furthermore, the exploration of its molecular interactions, signaling pathways, and expression patterns in cancerous tissues enhances our understanding of its function and relevance in oncogenesis. By investigating DKFZp547C195's mechanisms, researchers aim to uncover potential targets for innovative therapeutic interventions, ultimately contributing to improved patient outcomes in oncology. The ongoing research surrounding this protein reflects a broader trend in cancer biology, where the focus is shifting towards personalized medicine and targeted therapies that consider the unique molecular profiles of tumors. This highlights the importance of integrating molecular research with clinical applications to foster advancements in cancer diagnostics and treatments.
