Analytical Data
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基因名
VEGFR2
- Application
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别名
VEGFR2；FLK1；VEGFR2；Vascular endothelial growth factor receptor 2
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35918
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表达区间
20-762aa
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氨基酸序列
ASVGLPGDFLHPPKLSTQKDILTILANTTLQITCRGQRDLDWLWPNAQRDSEERVLVTECGGGDSIFCKTLTIPRVVGNDTGAYKCSYRDVDIASTVYVYVRDYRSPFIASVSDQHGIVYITENKNKTVVIPCRGSISNLNVSLCARYPEKRFVPDGNRISWDSEIGFTLPSYMISYAGMVFCEAKINDETYQSIMYIVVVVGYRIYDVILSPPHEIELSAGEKLVLNCTARTELNVGLDFTWHSPPSKSHHKKIVNRDVKPFPGTVAKMFLSTLTIESVTKSDQGEYTCVASSGRMIKRNRTFVRVHTKPFIAFGSGMKSLVEATVGSQVRIPVKYLSYPAPDIKWYRNGRPIESNYTMIVGDELTIMEVTERDAGNYTVILTNPISMEKQSHMVSLVVNVPPQIGEKALISPMDSYQYGTMQTLTCTVYANPPLHHIQWYWQLEEACSYRPGQTSPYACKEWRHVEDFQGGNKIEVTKNQYALIEGKNKTVSTLVIQAANVSALYKCEAINKAGRGERVISFHVIRGPEITVQPAAQPTEQESVSLLCTADRNTFENLTWYKLGSQATSVHMGESLTPVCKNLDALWKLNGTMFSNSTNDILIVAFQNASLQDQGDYVCSAQDKKTKKRHCLVKQLIILERMAPMITGNLENQTTTIGETIEVTCPASGNPTPHITWFKDNETLVEDSGIVLRDGNRNLTIRRVRKEDGGLYTCQACNVLGCARAETLFIIEGAQEKTNLE
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分子量
110 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Vascular endothelial growth factor receptor 2 (VEGFR2) is a crucial receptor that plays a significant role in angiogenesis, vascular permeability, and endothelial cell functions. It is primarily activated by its ligands, vascular endothelial growth factors (VEGFs), which are essential for both normal physiological processes and pathological conditions such as cancer, ischemic diseases, and inflammatory disorders. Given its pivotal role in promoting blood vessel formation and maintenance, VEGFR2 has emerged as a promising target for therapeutic interventions aimed at inhibiting excessive angiogenesis. Researchers have been developing recombinant VEGFR2 proteins to study their structure, function, and interactions with VEGFs and various inhibitors. These studies facilitate a better understanding of the signaling pathways involved in angiogenesis and help identify potential drug candidates for treating angiogenesis-related diseases. Moreover, recombinant VEGFR2 proteins serve as valuable tools in drug screening assays and biomarker development, contributing to the advancement of personalized medicine approaches. The exploration of VEGFR2 also extends to its involvement in tumor microenvironments, where its expression can influence cancer progression and metastasis. As such, the ongoing research on VEGFR2 recombinant proteins holds great promise for uncovering novel therapeutic strategies and enhancing our understanding of vascular biology and disease mechanisms.
