Cat: PA2000-6604

Recombinant Human CDH13 Protein,His

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Analytical Data

  • Gene name

    CDH13

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CAD13_HUMAN; Cadherin-13; CDH13; CDHH; H-cadherin; Heart cadherin; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P55290

  • Expression Region

    139-693aa

  • AA Sequence

    MASMTGGQQMGRGHHHHHHGNLYFQGGEFELSIVVSPILIPENQRQPFPR DVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREV IAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEG SPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGD IVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKN DHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNP GQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYG PSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSL QHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLA IDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGAS DKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNL PIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAG

  • Molecular Weight

    64 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CDH13, or Cadherin 13, is a member of the cadherin superfamily, which plays a crucial role in cell adhesion processes and is involved in various biological functions, including tissue development and maintenance. It is predominantly expressed in the central nervous system and has been linked to several neurodegenerative diseases, cardiovascular disorders, and certain types of cancer. Research into CDH13 has gained momentum due to its potential as a biomarker for disease diagnosis and a target for therapeutic interventions. Recombinant CDH13 proteins are increasingly being utilized in experimental studies to elucidate their functional roles and mechanisms of action in cellular processes. These proteins are generated using advanced biotechnological methods, allowing for the study of their structural properties and interactions with other molecules. By understanding the specific pathways and mechanisms through which CDH13 operates, researchers aim to uncover its contributions to disease pathology, thus paving the way for novel treatment strategies. In this context, the production and characterization of CDH13 recombinant proteins are vital for advancing our understanding of their biological significance and therapeutic potential.

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