Analytical Data
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基因名
RSAD2
- Application
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别名
2510004L01Rik; cig 33; CIG 5; cig-33; CIG-5; CIG33; CIG5; Cytomegalovirus induced gene 5 protein ; Cytomegalovirus-induced gene 5 protein; endoplasmic reticulum-associated; interferon-inducible; Radical S adenosyl methionine domain containing 2; Radical S-adenosyl methionine domain-containing protein 2; RSAD 2; Rsad2; RSAD2_HUMAN; RSDA-2; VIG 1; vig1; Viperin; Virus inhibitory protein; virus inhibitory protein endoplasmic reticulum associated interferon inducible
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WXG1
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表达区间
1-361 aa
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氨基酸序列
MWVLTPAAFA GKLLSVFRQP LSSLWRSLVP LFCWLRATFW LLATKRRKQQ LVLRGPDETK EEEEDPPLPT TPTSVNYHFT RQCNYKCGFC FHTAKTSFVL PLEEAKRGLL LLKEAGMEKI NFSGGEPFLQ DRGEYLGKLV RFCKVELRLP SVSIVSNGSL IRERWFQNYG EYLDILAISC DSFDEEVNVL IGRGQGKKNH VENLQKLRRW CRDYRVAFKI NSVINRFNVE EDMTEQIKAL NPVRWKVFQC LLIEGENCGE DALREAERFV IGDEEFERFL ERHKEVSCLV PESNQKMKDS YLILDEYMRF LNCRKGRKDP SKSILDVGVE EAIKFSGFDE KMFLKRGGKY IWSKADLKLD W
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分子量
42.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RSAD2, also known as radical S-adenosyl methionine domain 2, is a protein that plays a critical role in the innate immune response, particularly during viral infections. It is recognized for its ability to interfere with viral replication and promote antiviral defense mechanisms. Upon viral infection, RSAD2 expression is upregulated, suggesting its involvement in the cellular response to pathogen invasion. Research indicates that RSAD2 possesses a unique antiviral activity by promoting the formation of specific cellular structures, including antiviral bodies and filaments, which can sequester viral components and inhibit their replication. Additionally, RSAD2 can modulate various signaling pathways linked to inflammation and immune response, further highlighting its importance in host defense. Studies have shown that RSAD2's mechanisms of action involve interactions with other proteins and cellular components that facilitate the restriction of viral spread and enhance the activity of immune cells. Given the increasing prevalence of viral infections and the need for effective therapeutic strategies, understanding the function, regulation, and potential applications of RSAD2 in antiviral therapies has become a significant focus in molecular and clinical research. Researchers are exploring the potential of RSAD2 as a target for drug development, as well as its utility as a biomarker for viral infections. The ongoing studies aim to elucidate the complex roles of RSAD2 in various pathogens, advancing our knowledge of immune responses and opening new avenues for innovative treatments in virology and infectious disease management.
