Analytical Data
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Gene name
RRS1
- Application
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Alternative Names
Homolog of yeast ribosome biogenesis regulator; Homolog of yeast ribosome biogenesis regulatory protein RRS1; KIAA0112; OTTHUMP00000227420; Ribosome biogenesis regulatory protein homolog; Ribosome biogenesis regulatory protein RRS1 homolog; RRR; rrs1; RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); RRS1_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15050
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Expression Region
1-365 aa
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AA Sequence
MEGQSVEELL AKAEQDEAEK LQRITVHKEL ELQFDLGNLL ASDRNPPTGL RCAGPTPEAE LQALARDNTQ LLINQLWQLP TERVEEAIVA RLPEPTTRLP REKPLPRPRP LTRWQQFARL KGIRPKKKTN LVWDEVSGQW RRRWGYQRAR DDTKEWLIEV PGNADPLEDQ FAKRIQAKKE RVAKNELNRL RNLARAHKMQ LPSAAGLHPT GHQSKEELGR AMQVAKVSTA SVGRFQERLP KEKVPRGSGK KRKFQPLFGD FAAEKKNQLE LLRVMNSKKP QLDVTRATNK QMREEDQEEA AKRRKMSQKG KRKGGRQGPG GKRKGGPPSQ GGKRKGGLGG KMNSGPPGLG GKRKGGQRPG GKRRK
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Molecular Weight
41.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RRS1 (Regulatory RNA Signaling 1) is a protein that has garnered significant attention in the field of molecular biology and genetics due to its pivotal role in regulating cellular responses to environmental stresses and its involvement in ribosome biogenesis. Emerging research highlights RRS1's function in the assembly and maturation of ribosomes, which are crucial for protein synthesis in all living organisms. Abnormalities in RRS1 expression or function can lead to various diseases, including cancer, highlighting the importance of understanding its underlying mechanisms. Various studies have also suggested that RRS1 may interact with different signaling pathways, making it a potential target for therapeutic intervention. Furthermore, the ability to produce RRS1 as a recombinant protein using techniques such as recombinant DNA technology is essential for elucidating its structure and function, as well as for screening potential inhibitors. This research could lead to novel insights into ribosomal function and the cellular stress response, ultimately paving the way for new strategies in disease treatment. Investigating RRS1 not only enriches our knowledge of ribosome biology but also offers broad implications for understanding cellular homeostasis under stress and its subsequent effects on health and disease.
