Analytical Data
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基因名
RNF38
- Application
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别名
RING finger protein 38; Rnf38; RNF38_HUMAN; RP11-84P7.4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H0F5
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表达区间
1-515 aa
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氨基酸序列
MACKISPGAN SASLPGHPNK VICERVRLQS LFPLLPSDQN TTVQEDAHFK AFFQSEDSPS PKRQRLSHSV FDYTSASPAP SPPMRPWEMT SNRQPPSVRP SQHHFSGERC NTPARNRRSP PVRRQRGRRD RLSRHNSISQ DENYHHLPYA QQQAIEEPRA FHPPNVSPRL LHPAAHPPQQ NAVMVDIHDQ LHQGTVPVSY TVTTVAPHGI PLCTGQHIPA CSTQQVPGCS VVFSGQHLPV CSVPPPMLQA CSVQHLPVPY AAFPPLISSD PFLIHPPHLS PHHPPHLPPP GQFVPFQTQQ SRSPLQRIEN EVELLGEHLP VGGFTYPPSA HPPTLPPSAP LQFLTHDPLH QEVSFGVPYP PFMPRRLTGR SRYRSQQPIP PPPYHPSLLP YVLSMLPVPP AVGPTFSFEL DVEDGEVENY EALLNLAERL GEAKPRGLTK ADIEQLPSYR FNPNNHQSEQ TLCVVCMCDF ESRQLLRVLP CNHEFHAKCV DKWLKANRTC PICRADASEV HRDSE
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分子量
57.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RNF38 (RING finger protein 38) is a member of the RING finger family of E3 ubiquitin ligases, known for its critical role in regulating protein degradation and various cellular processes through ubiquitination. Research into RNF38 has gained momentum due to its implications in cancer biology and cellular stress responses. Recent studies have highlighted its involvement in modulating key signaling pathways, influencing cell proliferation, apoptosis, and DNA damage response. Furthermore, aberrations in RNF38 expression or function have been linked to various malignancies, suggesting a potential role in tumorigenesis and cancer progression. The recombinant protein of RNF38 is of significant interest for understanding its structure-function relationships and molecular mechanisms. By producing RNF38 in a recombinant form, researchers can investigate its biochemical properties, interactions with substrate proteins, and its influence on the ubiquitin-proteasome system. This research is not only important for elucidating the fundamental biology of RNF38 itself but also holds promise for developing novel therapeutic strategies targeting E3 ligases in cancer treatment. Overall, the study of RNF38 recombinant protein serves as a crucial step in uncovering its biological roles and therapeutic potential.
