Analytical Data
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Gene name
trxC
- Application
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Alternative Names
trxC；trx；trxC；Thioredoxin
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Species
E.coli
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P0AGG4
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Expression Region
1-139aa
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AA Sequence
MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGETLDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRFGIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL
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Molecular Weight
17.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of trxC recombinant protein primarily revolves around its role in cellular redox regulation and its potential applications in biotechnology and medicine. Thioredoxin (Trx) is a crucial protein involved in maintaining cellular redox balance, regulating various physiological processes, including cell proliferation, differentiation, and apoptosis. The trxC gene encodes a specific thioredoxin that is often studied for its antioxidant properties and ability to donate electrons, thereby protecting cells from oxidative stress. Recent research has highlighted the importance of trxC in various disease contexts, particularly in cancer, where altered redox homeostasis can promote tumor growth and resistance to therapies. Additionally, trxC has been explored as a potential therapeutic agent, with studies investigating its role in enhancing immune responses and its use in drug delivery systems. The recombinant expression of trxC allows for the production of this protein in sufficient quantities for detailed biochemical and structural studies, which can lead to a better understanding of its functions and mechanisms. Furthermore, modifications to the trxC protein can enhance its stability and activity, paving the way for innovative applications in therapeutic interventions and industrial processes. Overall, the investigation of trxC recombinant protein holds promise for developing novel strategies to combat diseases associated with redox imbalances, while also contributing to the broader fields of molecular biology and protein engineering.
