Cat: PA2000-6169

Recombinant Human C20orf186 Protein,GST

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Analytical Data

  • Gene name

    C20orf186

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BPI fold-containing family B member 4; Bpifb4; C20orf186; dJ726C3.5; Gm1006; Ligand-binding Protein RY2G5; Long palate; lung and nasal epithelium carcinoma-associated Protein 4; LPLC4_HUMAN; Lplunc4

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P59827

  • Expression Region

    1-575aa

  • AA Sequence

    MLQQSDALHSALREVPLGVGDIPYNDFHVRGPPPVYTNGKKLDGIYQYGHIETNDNTAQLGGKYRYGEILESEGSIRDLRNSGYRSAENAYGGHRGLGRYRAAPVGRLHRRELQPGEIPPGVATGAVGPGGLLGTGGMLAADGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTRVAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRGLLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLPLVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSANFLGSVLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSVMLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTEGDKLMIDAKLEKTSLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADIDVLEDLLVLSA

  • Molecular Weight

    90.2 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C20orf186, also known as the chromosome 20 open reading frame 186, is a relatively less-studied protein that has gained attention in recent years due to its potential role in various biological processes and diseases. Initial research indicated that C20orf186 might be involved in cellular functions such as proliferation, apoptosis, and immune responses. Its expression patterns and potential implications in cancer biology, particularly in different types of tumors, have spurred scientific interest. Moreover, its location on chromosome 20 suggests a possible involvement in genetic disorders linked to chromosomal abnormalities. Investigating the recombinant form of C20orf186 is crucial for understanding its structure-function relationships and interactions with other cellular proteins. By producing and purifying the recombinant protein, researchers aim to elucidate its biochemical properties and functional roles in cellular mechanisms. Furthermore, studies utilizing this recombinant protein could provide insights into its potential as a biomarker or therapeutic target, paving the way for future investigations in the context of disease pathology and treatment strategies. Understanding C20orf186's function may ultimately contribute to the broader field of genomic research and aid in the development of innovative approaches to manage diseases associated with its dysregulation.

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