Analytical Data
-
基因名
RAG1AP1
- Application
-
别名
SLC50A1; RAG1AP1; SCP; Sugar transporter SWEET1; HsSWEET1; RAG1-activating protein 1; Solute carrier family 50 member 1; Stromal cell protein
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BRV3
-
表达区间
1-167 aa
-
氨基酸序列
MEAGGFLDSLIYGACVVFTLGMFSAGLSDLRHMRMTRSVDNVQFLPFLTTEVNNLGWLSYGALKGDGILIVVNTVGAALQTLYILAYLHYCPRKAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDPYIMVSNFPGIVTSFIRFWLFWKYPQEQDRNYWLLQT
-
分子量
45.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAG1AP1, or RAG1-activating protein 1, is a critical component in the V(D)J recombination process, a fundamental mechanism for generating diverse antigen receptors in lymphocytes. This protein plays a pivotal role in activating the Recombinase-Activating Gene (RAG) proteins, which are essential for the rearrangement of immunoglobulin and T-cell receptor genes. The study of RAG1AP1 is particularly significant as it helps in understanding the immune system's adaptability and the development of lymphoid malignancies. Mutations or dysregulation in RAG1AP1 can lead to severe immunodeficiencies or contribute to the pathogenesis of various cancers, highlighting its importance in both basic immunology and clinical implications. Research efforts are increasingly focusing on the molecular mechanisms underlying RAG1AP1's function, interactions with other cellular proteins, and its potential as a therapeutic target. Understanding RAG1AP1 could provide insights into novel strategies for treating immune disorders and cancers, underscoring its relevance in both health and disease. Continued exploration of RAG1AP1 and its pathways stands to illuminate the complexities of immune system functioning and the broader implications of these processes within the field of medical research.
