Analytical Data
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Gene name
RABL2A
- Application
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Alternative Names
FLJ78724; MGC117180; OTTHUMP00000045491; OTTHUMP00000045492; OTTHUMP00000045493; OTTHUMP00000203788; OTTHUMP00000203792; Rab-like protein 2A; RABL2A; RBL2A_HUMAN; RP11-395L14.2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UBK7
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Expression Region
1-228 aa
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AA Sequence
MAEDKTKPSE LDQGKYDADD NVKIICLGDS AVGKSKLMER FLMDGFQPQQ LSTYALTLYK HTATVDGKTI LVDFWDTAGQ ERFQSMHASY YHKAHACIMV FDIQRKVTYR NLSTWYTELR EFRPEIPCIV VANKIDDINV TQKSFNFAKK FSLPLYFVSA ADGTNVVKLF NDAIRLAVSY KQNSQDFMDE IFQELENFSL EQEEEDVPDQ EQSSSIETPS EEVASPHS
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Molecular Weight
26.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RABL2A, a member of the RABL family of proteins, plays a critical role in the regulation of cell proliferation and differentiation. Initially identified in studies related to genome organization and nucleolar function, RABL2A has garnered attention for its involvement in various cellular processes, including ribosome biogenesis and mitotic spindle assembly. The protein is known to localize to the nucleolus and is essential for maintaining the integrity of nucleolar architecture. Its dysregulation has been implicated in several cancers, suggesting that RABL2A may serve as a potential biomarker or therapeutic target. Recent research has focused on elucidating the molecular mechanisms by which RABL2A contributes to tumorigenesis and cellular growth, with findings indicating that it interacts with key regulatory proteins and pathways. As such, understanding the functional role of RABL2A at a molecular level is crucial, not only for insight into basic cellular biology but also for the development of novel cancer therapies. The continued exploration of RABL2A's structure, function, and regulation will enhance our understanding of its role in health and disease.
