Analytical Data
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Gene name
LAT2
- Application
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Alternative Names
LAT2；LAT2；Large neutral amino acids transporter small subunit 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9GZY6
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Expression Region
27-243aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LAT2, or Lymphocyte Activation Triggering Protein 2, is a member of the LAT (Lymphocyte Activation Triggering) family, which plays a crucial role in T cell activation and signaling. The study of LAT2 is significant due to its potential implications in understanding immune responses and pathways associated with various diseases, including autoimmune disorders and cancers. LAT2 is primarily expressed in lymphoid tissues and is involved in the process of T cell receptor (TCR) signaling, which is essential for T cell development and activation. Research has shown that LAT2 interacts with several signaling molecules, thereby modulating various intracellular pathways that lead to T cell proliferation and cytokine production. Given its central role in immune system functioning, LAT2 presents a valuable target for therapeutic interventions aimed at modulating immune responses. Furthermore, investigating the structure and function of LAT2 can provide insights into the mechanisms of T cell-mediated immunity and tolerance. Understanding LAT2's dynamics during immune responses could pave the way for developing strategies to enhance immune responses against infections or tumors while also providing avenues to mitigate autoimmune reactions. As such, LAT2 represents a promising subject for further research into its biological roles, interactions, and potential for therapeutic exploitation in immunological contexts.
