Analytical Data
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基因名
Pkdcc
- Application
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别名
Pkdcc；SGK493；VLK；Extracellular tyrosine-Protein kinase PKDCC
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q504Y2
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表达区间
33-493aa
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氨基酸序列
PRPGQSPEPSPAPGPGRRGGRGELARQIRARYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLPRPRPPWARPLSDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYMGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGVRRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLEKVLHLYRSGQYLQNSTASSSTEYQCIPDSTIPQEDYRCWPSYHHGSCLLSVFNLAEAVDVCESHAQCRAFVVTNQTTWTGRQLVFFKTGWSQVVPDPNKTTYVKASG
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分子量
54.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Pkdcc, also known as Protein Kinase DCC, is a member of the protein kinase family that plays a crucial role in various cellular processes, including cell signaling, proliferation, and survival. The study of Pkdcc is particularly significant in the context of its potential implications in cancer biology and neurodegenerative diseases. Research has indicated that dysregulation of protein kinases, including Pkdcc, can lead to abnormal cellular behaviors that contribute to tumor progression and metastasis. As a result, understanding the structure and function of Pkdcc may uncover valuable insights into the molecular mechanisms underlying these diseases. Additionally, Pkdcc has been identified as a potential therapeutic target, raising the need for the development of recombinant Pkdcc proteins for both functional studies and drug development. Recombinant protein technology allows for the generation of large quantities of pure, active Pkdcc, enabling researchers to investigate its biochemical properties and interactions with other cellular components. Furthermore, studying the effects of Pkdcc in various model systems can provide a deeper understanding of its physiological roles and potential as a target in therapeutic contexts. Therefore, research focusing on the recombinant expression and characterization of Pkdcc is vital for unveiling its functional significance and developing strategies for combating diseases associated with its dysfunction.
