Cat: PAX2000-10371

Recombinant Human PLAG1 Protein,GST

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Analytical Data

  • Gene name

    PLAG1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Zinc finger protein PLAG1. Pleiomorphic adenoma gene 1 protein

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q6DJT9

  • Expression Region

    1-500 aa

  • AA Sequence

    MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ

  • Molecular Weight

    55 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PLAG1 (pleomorphic adenoma gene 1) is a transcription factor known to play a crucial role in cell growth, differentiation, and oncogenesis. It is primarily associated with pleomorphic adenoma, a common benign tumor of the salivary glands, where PLAG1 gene rearrangements often lead to its overexpression. Research into PLAG1-recombinant proteins has gained momentum due to their potential implications in cancer biology and therapeutic applications. Understanding the structural and functional characteristics of PLAG1 can provide insights into its role in tumorigenesis and cellular signaling pathways. Moreover, PLAG1 can serve as a valuable biomarker for diagnosing related neoplasms. The development of PLAG1-recombinant proteins enables the exploration of its biochemical activity, interactions with other cellular proteins, and regulatory mechanisms. This research not only furthers the understanding of salivary gland tumors but may also uncover broader implications for other cancers driven by transcriptional dysregulation. Overall, the study of PLAG1-recombinant proteins is critical for developing diagnostic tools and targeted therapies, addressing the urgent need for advancements in cancer treatment strategies.

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