Analytical Data
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Gene name
TRPT1
- Application
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Alternative Names
TRPT1；tRNA 2'-phosphotransferase 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86TN4
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Expression Region
1-253aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMNFSGG GRQEAAGSRG RRAPRPREQD RDVQLSKALS YALRHGALKL GLPMGADGFV PLGTLLQLPQ FRGFSAEDVQ RVVDTNRKQR FALQLGDPST GLLIRANQGH SLQVPKLELM PLETPQALPP MLVHGTFWKH WPSILLKGLS CQGRTHIHLA PGLPGDPGII SGMRSHCEIA VFIDGPLALA DGIPFFRSAN GVILTPGNTD GFLLPKYFKE ALQLRPTRKP LSLAGDEETE CQSSPKHSSR ERRRIQQ
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Molecular Weight
30 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRPT1 (Tryptophanyl-tRNA synthetase 1) is a key enzyme involved in protein synthesis, specifically responsible for the attachment of tryptophan to its corresponding transfer RNA (tRNA). This enzyme plays a critical role in the translational process, influencing both the accuracy and efficiency of protein synthesis. Research on TRPT1 has gained importance due to its potential implications in various biological processes and diseases. Alterations or mutations in this enzyme can lead to misfolded proteins and contribute to the development of several disorders, including neurodegenerative diseases, cancer, and metabolic syndromes. Additionally, TRPT1 is implicated in regulating cellular responses to stress, highlighting its significance in maintaining cellular homeostasis. Recent studies have focused on the structural and functional characterization of TRPT1, facilitating a deeper understanding of its enzymatic mechanisms and interactions within the ribosomal complex. Understanding TRPT1's biochemical properties and its regulatory networks may pave the way for novel therapeutic strategies targeting diseases associated with protein synthesis dysregulation. The exploration of TRPT1 as a potential biomarker for specific pathologies further underscores its relevance in biomedical research. Overall, the study of TRPT1 and its recombinant forms holds significant promise for advancing our knowledge of protein synthesis and its impact on human health.
