Analytical Data
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基因名
OVOL1
- Application
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别名
hOvo1; Ovo homolog like 1; Ovo like 1(Drosophila); Ovo. Drosophila. homolog-like. 1; Ovol1; OVOL1_HUMAN; Putative transcription factor Ovo like 1; Putative transcription factor Ovo-like 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14753
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表达区间
1-267 aa
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氨基酸序列
MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP LLRKTSKKVA VALQNTVTSL LQGSPHL
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分子量
30.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OVOL1, or Ovo-like protein 1, is a transcription factor belonging to the Ovo-like family, playing a vital role in embryonic development and cellular differentiation. This protein is primarily expressed in the testis, ovary, and various embryonic tissues, highlighting its importance in germ cell development and organogenesis. Recent studies have demonstrated that OVOL1 regulates key genes involved in the processes of epithelial-to-mesenchymal transition (EMT), a critical event in development and cancer metastasis. Given its significant functional roles, researchers have increasingly focused on OVOL1 as a potential biomarker for certain cancers and a target for therapeutic interventions. The recombinant production of OVOL1 is crucial for understanding its structure-function relationship and interactions with other molecular players involved in cell fate decisions. By utilizing various expression systems, such as bacterial or eukaryotic systems, scientists aim to generate large quantities of functional OVOL1 protein. This enables detailed biochemical and biophysical characterization, facilitating insights into its regulatory mechanisms and potential applications in regenerative medicine and cancer therapy. The ongoing research into OVOL1 continues to unravel its intricate roles in both normal development and pathological conditions, emphasizing its potential impact on future therapeutic strategies.
