Analytical Data
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基因名
ITPR2
- Application
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别名
ITPR2；Inositol 1.4.5-trisphosphate receptor type 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14571
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表达区间
全长
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氨基酸序列
full
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分子量
308 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITPR2 (Inositol 1,4,5-trisphosphate receptor type 2) is a crucial protein involved in intracellular calcium signaling, playing a significant role in various physiological processes such as muscle contraction, neurotransmitter release, and cell proliferation. The study of ITPR2 has gained attention due to its implications in several pathological conditions, including cardiac dysfunction, neurological disorders, and cancer. Its dysfunctional signaling pathways can lead to altered calcium homeostasis, contributing to disease progression. Recent research has focused on the structural and functional characterization of ITPR2, including its interactions with other proteins and its regulatory mechanisms. The development of recombinant ITPR2 proteins has enabled scientists to explore these aspects in detail, providing insights into the receptor's role in health and disease. Understanding ITPR2's molecular dynamics and its broader biological significance could pave the way for potential therapeutic interventions targeting calcium signaling pathways, emphasizing the importance of continued research in this area.
