Analytical Data
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基因名
NEUROD2
- Application
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别名
bHLHa1; class A basic helix loop helix protein 1; Class A basic helix-loop-helix protein 1; NDF2_HUMAN; NDR2; NDRF; neuroD related factor; NeuroD-related factor; NeuroD2; neurogenic basic helix loop helix protein; neurogenic differentiation 2; Neurogenic differentiation factor 2; neuronal differentiation 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15784
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表达区间
1-382 aa
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氨基酸序列
MLTRLFSEPG LLSDVPKFAS WGDGEDDEPR SDKGDAPPPP PPAPGPGAPG PARAAKPVPL RGEEGTEATL AEVKEEGELG GEEEEEEEEE EGLDEAEGER PKKRGPKKRK MTKARLERSK LRRQKANARE RNRMHDLNAA LDNLRKVVPC YSKTQKLSKI ETLRLAKNYI WALSEILRSG KRPDLVSYVQ TLCKGLSQPT TNLVAGCLQL NSRNFLTEQG ADGAGRFHGS GGPFAMHPYP YPCSRLAGAQ CQAAGGLGGG AAHALRTHGY CAAYETLYAA AGGGGASPDY NSSEYEGPLS PPLCLNGNFS LKQDSSPDHE KSYHYSMHYS ALPGSRPTGH GLVFGSSAVR GGVHSENLLS YDMHLHHDRG PMYEELNAFF HN
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分子量
41.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NEUROD2, or Neuronal Differentiation 2, is a crucial transcription factor that plays an essential role in the development and differentiation of neuronal cells. Research on NEUROD2 has garnered significant attention due to its implications in neurogenesis and potential involvement in neurological disorders. NEUROD2 is known to regulate the expression of genes associated with neuronal identity and function, contributing to the maturation and survival of neurons. Studies have shown that NEUROD2 can influence the plasticity of neuronal circuits, making it a key player in processes such as learning and memory. Additionally, its expression patterns are observed to be altered in various neurodegenerative diseases, including Alzheimer's and Parkinson's, highlighting its potential as a biomarker for these conditions. The development and characterization of recombinant NEUROD2 proteins enable researchers to investigate its structure-function relationships and interactions with other molecular partners. Recombinant proteins allow for detailed studies of NEUROD2's role in transcriptional regulation and its capacity to influence neuronal behavior in vitro and in vivo. Exploring the biological functions of NEUROD2 through recombinant proteins can thus pave the way for novel therapeutic strategies aimed at treating neurological disorders, enhancing neuronal regeneration, and understanding the underlying mechanisms of neurodevelopmental processes. Overall, NEUROD2 stands as a promising candidate in neurobiology, and its recombinant forms are vital tools for advancing our understanding of neuronal development and associated pathologies.
