Analytical Data
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Gene name
IGF2
- Application
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Biological Activity
1.The ED50 is <20>5 × 104 units/mg. 2.Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is 3.658 ng/mL, corresponding to a specific activity is 2.733×105 units/mg. Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is 3.658 ng/mL, corresponding to a specific activity is 2.733×105 units/mg.
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Alternative Names
rHuIGF-2; Somatamedin A; IGF-II
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 95% as determined by reducing SDS-PAGE.
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Uniprot
P01344-1
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Expression Region
A25-E91
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Protein Length
Full Length of IGF2
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Molecular Weight
8-11 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Insulin-like growth factor 2 (IGF2) is a crucial peptide hormone that plays a significant role in growth and development, particularly in fetal growth and cellular proliferation. Research on IGF2 recombinant proteins has gained traction due to their potential therapeutic applications in various conditions, including growth disorders, cancer, and metabolic diseases. The expression and modulation of IGF2 can influence cellular processes such as apoptosis, differentiation, and metabolism, making it a target of interest in both basic and clinical research. Advances in biotechnology have enabled the production of recombinant IGF2 with enhanced stability and bioavailability, allowing for more effective therapeutic interventions. Additionally, the role of IGF2 in the epigenetic regulation of gene expression during development has opened new avenues for exploring its functions in tumorigenesis and other pathologies. Understanding the molecular mechanisms governing IGF2's actions and its signaling pathways could lead to the development of novel strategies for disease prevention and treatment. Overall, the study of IGF2 recombinant proteins represents a promising field in biomedical research, aiming to harness the growth-promoting and metabolic functions of this growth factor for therapeutic benefits.











