Cat: PA1000-2191

Recombinant Human NRIP3 Protein,His

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Analytical Data

  • Gene name

    NRIP3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NRIP3;C11orf14;Nuclear receptor-interacting Protein 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NQ35

  • Expression Region

    1-241aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMFYSGLL TEGGRKETDM REAASLRQQR RMKQAVQFIH KDSADLLPLD GLKKLGSSKD MQPHNILQRR LMETNLSKLR SGPRVPWASK TNKLNQAKSE GLKKSEEDDM ILVSCQCAGK DVKALVDTGC LYNLISLACV DRLGLKEHVK SHKHEGEKLS LPRHLKVVGQ IEHLVITLGS LRLDCPAAVV DDNEKNLSLG LQTLRSLKCI INLDKHRLIM GKTDKEEIPF VETVSLNEDN TSEA

  • Molecular Weight

    29 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NRIP3, or nuclear receptor interacting protein 3, is a member of the NRIP family that plays a crucial role in regulating various cellular processes, including transcriptional activation, signal transduction, and cellular stress responses. Research on NRIP3 has gained significant attention due to its involvement in critical biological pathways and its potential implications in disease mechanisms, particularly in cancer and metabolic disorders. Studies have shown that NRIP3 interacts with several nuclear receptors and transcription factors, modulating their activity and influencing gene expression patterns. As a result, understanding the molecular mechanisms governing NRIP3 function is essential for elucidating its role in homeostasis and pathology. The recombination and expression of NRIP3 as a recombinant protein allows for the investigation of its structural and functional properties, facilitating studies on protein-protein interactions, binding affinities, and intracellular signaling pathways. Moreover, the characterization of NRIP3 in vitro can provide insights into its therapeutic potential and significance as a biomarker for various diseases. Given the growing body of evidence linking NRIP3 to critical biological functions and disease states, research focused on this protein could pave the way for novel therapeutic strategies and enhance our understanding of molecular biology in health and disease contexts. Thus, the study of NRIP3 recombinant protein represents a promising area of investigation that may contribute to advances in both fundamental science and clinical applications.

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