Analytical Data
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基因名
D2D
- Application
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别名
D2D；LEP12；SPRL1A；Late cornified envelope Protein 2D
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TA82
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表达区间
1-110aa
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氨基酸序列
MSCQQNQQQC QPPPKCPPKC TPKCPPKCPP KCPPQCPAPC SPAVSSCCGP SSGSCCGPSS GGCCSSGGGG CCLSHHRPRL FHRRRHQSPD CCESEPSGAS GCCHSSGGCC
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分子量
11.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
D2D, or the D2 dopamine receptor, is a critical component in the central nervous system, primarily involved in regulating various neurobiological processes such as mood, cognition, and motor control. Research on D2D recombinant proteins has garnered significant attention due to their potential implications in understanding and treating psychiatric disorders, such as schizophrenia and depression, where dopamine signaling is often disrupted. The ability to produce D2D as a recombinant protein allows for detailed studies on its structure, function, and interactions with other cellular components. This research plays a crucial role in drug development, as targeted therapies that modulate D2D activity can lead to more effective treatments with fewer side effects. Furthermore, the investigation of D2D’s pharmacological properties, such as ligand binding and receptor activation, enhances our understanding of receptor biology and the mechanisms underlying various neuropsychiatric conditions. Ultimately, the study of D2D recombinant proteins contributes to the broader field of neuropharmacology and aids in the quest for novel therapeutic strategies that can transform the management of dopamine-related disorders.
