Analytical Data
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Gene name
KRT39
- Application
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Alternative Names
KRT39; KA35; Keratin; type I cytoskeletal 39; Cytokeratin-39; CK-39; Keratin-39; K39; Type I hair keratin Ka35
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6A163
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Expression Region
1-491aa
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AA Sequence
MDTKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHVQPCFIIRPAKV
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Molecular Weight
80.41 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KRT39, a member of the keratin family, is a type I keratin predominantly expressed in epithelial cells, playing a crucial role in maintaining cellular structure and function. The study of KRT39 and its recombinant protein has gained attention due to its potential implications in various pathological conditions, including skin disorders and cancers. Keratins, including KRT39, are essential for the formation of the cytoskeletal network, providing mechanical resilience to tissues and participating in crucial cellular processes such as differentiation, proliferation, and apoptosis. Recent advances in molecular biology and biotechnology have facilitated the production of recombinant proteins, allowing researchers to investigate the functional properties of KRT39 in vitro and in vivo. Understanding the structure-function relationship of KRT39 could uncover its role in cellular dynamics and its contribution to disease mechanisms. Furthermore, the development of KRT39-based biosensors or therapeutic targets might present novel approaches for treating disorders associated with keratin dysfunction. Thus, the exploration of KRT39 recombinant protein focuses not only on its basic biological functions but also on its potential translational applications in regenerative medicine and oncology, highlighting the importance of this protein in health and disease.
