Analytical Data
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基因名
KRT39
- Application
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别名
KRT39; KA35; Keratin; type I cytoskeletal 39; Cytokeratin-39; CK-39; Keratin-39; K39; Type I hair keratin Ka35
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6A163
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表达区间
1-491aa
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氨基酸序列
MDTKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHVQPCFIIRPAKV
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分子量
80.41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT39, a member of the keratin family, is a type I keratin predominantly expressed in epithelial cells, playing a crucial role in maintaining cellular structure and function. The study of KRT39 and its recombinant protein has gained attention due to its potential implications in various pathological conditions, including skin disorders and cancers. Keratins, including KRT39, are essential for the formation of the cytoskeletal network, providing mechanical resilience to tissues and participating in crucial cellular processes such as differentiation, proliferation, and apoptosis. Recent advances in molecular biology and biotechnology have facilitated the production of recombinant proteins, allowing researchers to investigate the functional properties of KRT39 in vitro and in vivo. Understanding the structure-function relationship of KRT39 could uncover its role in cellular dynamics and its contribution to disease mechanisms. Furthermore, the development of KRT39-based biosensors or therapeutic targets might present novel approaches for treating disorders associated with keratin dysfunction. Thus, the exploration of KRT39 recombinant protein focuses not only on its basic biological functions but also on its potential translational applications in regenerative medicine and oncology, highlighting the importance of this protein in health and disease.
