Analytical Data
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基因名
P-cadherin
- Application
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别名
P-cadherin；CDHP；Cadherin-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22223
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表达区间
25-654aa
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氨基酸序列
EPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPGQEPALFSTDNDDFT VRNGETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPF PQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLD REEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSV LEGVLPGTSVMQMTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHR STGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDN APMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDG DHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTST ATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKI SYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNG SPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSP HTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDH GNKEQLTVIRATVCDCHGHVETCPGPWKGGVDHHHHHH
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分子量
70 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
P-cadherin, a member of the cadherin family of cell adhesion molecules, plays a crucial role in maintaining tissue architecture and cellular interactions. It is primarily expressed in specific types of epithelial tissues and has been implicated in various physiological and pathological processes, including development, wound healing, and cancer progression. The study of P-cadherin is vital because its dysregulation is often associated with increased tumorigenicity and metastasis in several cancers, such as breast and prostate cancer. Research into recombinant P-cadherin protein focuses on understanding its structural and functional properties, as well as its role in cell-cell adhesion mechanisms. By producing and characterizing recombinant P-cadherin, scientists aim to elucidate the molecular pathways it influences, provide insights into its interaction with other proteins, and identify potential targets for therapeutic intervention. The recombinant protein can also be used in various applications, including functional assays and drug screening, to explore its potential as a biomarker or target in cancer therapy. Overall, the study of recombinant P-cadherin represents a promising avenue for advancing our knowledge of cell adhesion dynamics and their implications in health and disease.
