Analytical Data
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基因名
KIAA1530
- Application
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别名
hypothetical protein LOC57654; K1530_HUMAN; KIAA1530; Uncharacterized protein KIAA1530; UV stimulated scaffold protein A; UVSS3; UVSSA
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q2YD98
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表达区间
1-709aa
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氨基酸序列
MDQKLSKLVE ELTTSGEPRL NPEKMKELKK ICKSSEEQLS RAYRLLIAQL TQEHAEIRLS AFQIVEELFV RSHQFRMLVV SNFQEFLELT LGTDPAQPLP PPREAAQRLR QATTRAVEGW NEKFGEAYKK LALGYHFLRH NKKVDFQDTN ARSLAERKRE EEKQKHLDKI YQERASQAER EMQEMSGEIE SCLTEVESCF RLLVPFDFDP NPETESLGMA SGMSDALRSS CAGQVGPCRS GTPDPRDGEQ PCCSRDLPAS AGHPRAGGGA QPSQTATGDP SDEDEDSDLE EFVRSHGLGS HKYTLDVELC SEGLKVQENE DNLALIHAAR DTLKLIRNKF LPAVCSWIQR FTRVGTHGGC LKRAIDLKAE LELVLRKYKE LDIEPEGGER RRTEALGDAE EDEDDEDFVE VPEKEGYEPH IPDHLRPEYG LEAAPEKDTV VRCLRTRTRM DEEVSDPTSA AAQLRQLRDH LPPPSSASPS RALPEPQEAQ KLAAERARAP VVPYGVDLHY WGQELPTAGK IVKSDSQHRF WKPSEVEEEV VNADISEMLR SRHITFAGKF EPVQHWCRAP RPDGRLCERQ DRLKCPFHGK IVPRDDEGRP LDPEDRAREQ RRQLQKQERP EWQDPELMRD VEAATGQDLG SSRYSGKGRG KKRRYPSLTN LKAQADTARA RIGRKVFAKA AVRRVVAAMN RMDQKKHEKF SNQFNYALN
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分子量
80.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA1530, also known as KIF15, is a gene that encodes a member of the kinesin superfamily of motor proteins, which play essential roles in intracellular transport and mitotic processes. This protein is particularly interesting due to its involvement in various cellular functions, including spindle dynamics during cell division and the transport of cellular cargoes along microtubules. Research into KIAA1530 has gained momentum due to its potential implications in cancer biology; studies have suggested that it may be overexpressed in several types of cancer, contributing to tumor proliferation and metastasis. Additionally, KIAA1530 has been linked to cellular resilience in response to anti-cancer therapies, making it a candidate for targeted therapeutic strategies. The understanding of KIAA1530's structure, regulation, and pathway interactions is crucial for elucidating its role in normal cellular functions and disease states. Furthermore, the exploration of KIAA1530 recombinant proteins can provide insights into its molecular mechanisms, facilitate the discovery of small-molecule inhibitors, and enhance our understanding of mitotic regulation. As such, ongoing research into the biochemical characteristics and pathological significance of KIAA1530 continues to reveal its importance as a promising biomarker and therapeutic target in oncology. Overall, the study of KIAA1530 not only contributes to our understanding of basic cellular processes but also holds significant potential for advancing cancer treatment strategies.
