Analytical Data
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基因名
GPD1L
- Application
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别名
GPD1L;KIAA0089;Glycerol-3-phosphate dehydrogenase 1-like Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N335
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表达区间
1-351aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMAAAPLKVCIVGSGNWGSAVAKIIGNNVKK LQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSN LSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVI RLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFA RTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQI CYESRPVQEMLSCLQSHPEHT
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分子量
41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPD1L (Glycerol-3-Phosphate Dehydrogenase 1-Like) is an enzyme that plays a crucial role in lipid metabolism and energy production within cells. It is primarily involved in the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, thus participating in the glycerol phosphate shuttle, which is essential for the transport of electrons into the mitochondria for ATP synthesis. Recent studies have highlighted the significance of GPD1L in various physiological processes, including cardiac function and metabolic regulation. Mutations in the GPD1L gene have been associated with cardiac arrhythmias and other cardiovascular diseases, making it a key target for research in understanding the molecular mechanisms underlying these conditions. Additionally, the protein's involvement in the pathophysiology of metabolic disorders has opened avenues for exploring therapeutic interventions that could modulate its activity. The development of recombinant GPD1L proteins for experimental purposes has enabled researchers to investigate the functional properties of this enzyme in greater detail, contributing to our understanding of its role in metabolism and disease. As the global prevalence of metabolic syndromes and cardiovascular issues continues to rise, understanding the function and regulation of GPD1L could potentially yield novel insights into prevention and treatment strategies. Researchers are increasingly focusing on characterizing its biochemical properties, exploring its potential as a biomarker, and investigating the therapeutic implications of modulating its activity in various disease contexts. These efforts aim to unravel the complexities of GPD1L's role within the broader network of metabolic regulation and its potential impact on human health.












