Analytical Data
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Gene name
HNRNPG-T
- Application
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Alternative Names
Heterogeneous nuclear ribonucleoprotein G T; hnRNP G T; hnRNP G-T; HNRNPG T; HNRNPGT; HNRPGT; RBMX L2; RBMXL 2; RBMXL2; RMXL2_HUMAN; RNA binding motif protein X linked like 2; RNA-binding motif protein; Testes specific heterogenous nuclear ribonucleoprotein G T; Testis-specific heterogeneous nuclear ribonucleoprotein G-T; X-linked-like-2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75526
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Expression Region
1-392aa
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AA Sequence
MVEADRPGKLFIGGFNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKAAARDMNGKSLDGKAIKVAQATKPAFESSRRGPPPPRSRGRPRFLRGTRGGGGGPRRSPSRGGPDDDGGYAADFDLRPSRAPMPMKRGPPPRRVGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPLPPRRDPYLGPRDEGYSSRDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYGGRDRDYGDHLSRGSHREPFESYGELRGAAPGRGTPPSYGGGGRCEEYRGYSPDAYSGGRDSYSSSYGRSDRYSRGRHRVGRPDRGLSLSMERGCPPQRDSYSRSGCRVPRGGGRLGGRLERGGGRSRY
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Molecular Weight
69.52 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRNPG-T, a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, plays a crucial role in pre-mRNA processing and gene regulation, impacting various cellular processes such as RNA splicing, transport, and stability. Research has increasingly focused on HNRNPG-T due to its involvement in multiple biological functions and its implications in several diseases, including cancer and neurodegenerative disorders. The protein is known for its ability to interact with RNA and other proteins, influencing gene expression patterns and contributing to the regulation of alternative splicing events. Recent studies have highlighted the significance of HNRNPG-T in stress responses and its potential as a biomarker for cancer progression. Given its pivotal role in RNA metabolism, understanding the structural and functional dynamics of HNRNPG-T is essential for elucidating the molecular mechanisms underlying its activity. Additionally, investigations into its pathways may offer insights into therapeutic targets for disease intervention, making HNRNPG-T an important subject of biomedical research in the context of molecular biology and disease pathology.
