Analytical Data
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基因名
HNF4G
- Application
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别名
HNF4G; NR2A2Hepatocyte nuclear factor 4-gamma; HNF-4-gamma; Nuclear receptor subfamily 2 group A member 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14541
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表达区间
1-408aa
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氨基酸序列
MNTTDNGVNC LCAICGDRAT GKHYGASSCD GCKGFFRRSI RKSHVYSCRF SRQCVVDKDK RNQCRYCRLR KCFRAGMKKE AVQNERDRIS TRRSTFDGSN IPSINTLAQA EVRSRQISVS SPGSSTDINV KKIASIGDVC ESMKQQLLVL VEWAKYIPAF CELPLDDQVA LLRAHAGEHL LLGATKRSMM YKDILLLGNN YVIHRNSCEV EISRVANRVL DELVRPFQEI QIDDNEYACL KAIVFFDPDA KGLSDPVKIK NMRFQVQIGL EDYINDRQYD SRGRFGELLL LLPTLQSITW QMIEQIQFVK LFGMVKIDNL LQEMLLGGAS NDGSHLHHPM HPHLSQDPLT GQTILLGPMS TLVHADQIST PETPLPSPPQ GSGQEQYKIA ANQASVISHQ HLSKQKQL
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分子量
45.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNF4G (Hepatocyte Nuclear Factor 4 Gamma) is a transcription factor that plays a crucial role in the regulation of gene expression in liver and intestinal tissues. It is part of the nuclear receptor superfamily and is involved in various physiological processes, including lipid metabolism, glucose homeostasis, and the maintenance of intestinal epithelial integrity. Research into HNF4G has gained momentum due to its significant implications in metabolic disorders and its potential role as a therapeutic target for conditions such as diabetes, obesity, and liver diseases. The recombinant protein form of HNF4G is extensively studied to unravel its structure-function relationships and downstream gene targets, facilitating a deeper understanding of its biological mechanisms. This enables researchers to investigate its regulatory pathways and how alterations in HNF4G function may lead to disease. In addition to its fundamental biological significance, understanding HNF4G may also contribute to the development of novel strategies for disease prevention and treatment, highlighting the importance of recombinant protein studies in advancing our knowledge of metabolic health and disease. Overall, the investigation of HNF4G and its recombinant protein serves as a pivotal point for elucidating the complexities of metabolic regulation and opens avenues for innovative therapeutic interventions.
