Analytical Data
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基因名
stcE
- Application
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别名
stcE；C1IN；C1NH；Plasma protease C1 inhibitor
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种属
E.coli
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O82882
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表达区间
296-551aa
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氨基酸序列
ELLLHTIDIGMLTTPRDRFDFAKDKEAHREYFQTIPVSRMIVNNYAPLHLKEVMLPTGELLTDMDPGNGGWHSGTMRQRIGKELVSHGIDNANYGLNSTAGLGENSHPYVVAQLAAHNSRGNYANGIQVHGGSGGGGIVTLDSTLGNEFSHEVGHNYGLGHYVDGFKGSVHRSAENNNSTWGWDGDKKRFIPNFYPSQTNEKSCLNNQCQEPFDGHKFGFDAMAGGSPFSAANRFTMYTPNSSAIIQRFFENKAVF
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分子量
33.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The stcE protein is a significant virulence factor produced by certain pathogenic strains of Escherichia coli, especially Enterohemorrhagic E. coli (EHEC) and Enterotoxigenic E. coli (ETEC). This protein is involved in the bacterium's ability to cause severe gastrointestinal diseases, including diarrhea and hemolytic uremic syndrome (HUS). Research into the stcE protein has gained momentum due to the increasing incidence of E. coli-related outbreaks and the public health challenges they pose. Studies suggest that stcE plays a critical role in the manipulation of host cell processes, facilitating bacterial survival and enhancing the pathogen's ability to evade the host immune response. Thus, understanding the molecular mechanisms of stcE is crucial for developing potential therapeutic strategies and vaccines. The production of recombinant stcE protein allows for detailed characterization of its properties and interactions with host cells, providing insights into its role in pathogenesis. Furthermore, the investigation of stcE may contribute to broader research on bacterial virulence factors and lead to innovative approaches to combat E. coli infections. This research area underscores the importance of tackling foodborne pathogens and highlights the need for continued exploration of bacterial proteins that contribute to disease.
