Analytical Data
-
基因名
LOXL4
- Application
-
别名
LOXL4；LOXC；Lysyl oxidase homolog 4
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96JB6
-
表达区间
25-756aa
-
氨基酸序列
QSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
-
分子量
85.9kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human EXOSC8 Protein，His
Cat：PA1000-1062
Recombinant E.coli mutS Protein，His
Cat：PA2000-3815
Recombinant Human EXOSC7 Protein，His
Cat：PA1000-1061
Protein Description
LOXL4 (Lysyl Oxidase-like 4) is a member of the lysyl oxidase (LOX) family, which plays a crucial role in extracellular matrix (ECM) remodeling and has been implicated in various physiological and pathological processes. Research on LOXL4 has gained momentum due to its potential involvement in fibrotic diseases, cancer progression, and cardiovascular disorders. Unlike other LOX family members, LOXL4 exhibits unique substrate specificity and tissue distribution, suggesting distinct biological functions. Its expression is tightly regulated during development, and aberrant expression has been associated with tissue fibrosis and tumorigenesis. Recombination protein studies of LOXL4 aim to elucidate its enzymatic mechanisms and interactions with ECM components, as well as its regulatory pathways. Understanding LOXL4’s structure and function could reveal novel therapeutic targets for managing diseases characterized by abnormal ECM remodeling. Therefore, LOXL4 recombinant protein research is pivotal for advancing our knowledge of ECM biology and developing strategies to combat related diseases. By employing various experimental techniques such as enzyme assays, protein-protein interaction assays, and in vivo animal models, researchers aim to dissect the multifaceted roles of LOXL4 in health and disease, thereby uncovering its potential as a biomarker or therapeutic target in clinical settings.
