Analytical Data
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基因名
EDN2
- Application
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别名
EDN2;Endothelin-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P20800
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表达区间
25-178aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSQAAATLE QPASSSHAQG THLRLRRCSC SSWLDKECVY FCHLDIIWVN TPEQTAPYGL GNPPRRRRRS LPRRCQCSSA RDPACATFCL RRPWTEAGAV PSRKSPADVF QTGKTGATTG ELLQRLRDIS TVKSLFAKRQ QEAMREPRST HSRWRKR
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分子量
20 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EDN2, or Endothelin-2, is a member of the endothelin family of peptides, which are known to play crucial roles in various physiological and pathological processes, including vascular tone regulation, smooth muscle contraction, and cell proliferation. The interest in EDN2 has surged due to its implications in cardiovascular diseases, pulmonary conditions, and developmental biology. Unlike the other endothelins, EDN2 exhibits distinct expression patterns and biological activities, warranting focused research to elucidate its specific roles. Advances in recombinant protein technology have allowed for the production of EDN2 in heterologous systems, providing an opportunity to study its structure-function relationship in detail. Understanding EDN2’s signaling mechanisms can unveil potential therapeutic targets for diseases where endothelin pathways are dysregulated. Furthermore, the exploration of EDN2's interactions with its receptors and other biological molecules is crucial for developing targeted interventions. Overall, the study of EDN2 recombinant protein not only enhances our understanding of endothelin biology but also holds promise for clinical applications in treating various disorders associated with endothelin signaling dysregulation.
