Analytical Data
-
Gene name
LRRFIP1
- Application
-
Alternative Names
LRRFIP1；FLIL；Protein flightless-1 homolog
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q32MZ4
-
Expression Region
1-314aa
-
AA Sequence
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQSLSTCSLDR
-
Molecular Weight
40.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LRRFIP1 (leucine-rich repeat flightless-interacting protein 1) is a crucial regulator involved in various cellular processes, including cell signaling, transcriptional regulation, and cytoskeletal dynamics. Research has shown that LRRFIP1 plays a significant role in the immune response, particularly in T cell activation and differentiation. Its interactions with other proteins, such as the flightless-1 protein, suggest that it may be integral to processes such as cell migration and development. Given its involvement in cancer biology, where altered expression levels of LRRFIP1 have been associated with tumor progression and metastasis, the recombinant expression of LRRFIP1 is of great interest. The study of LRRFIP1 through recombinant protein technology allows for detailed investigations of its structure-function relationships and interactions with binding partners, shedding light on its potential as a therapeutic target. Moreover, understanding the molecular mechanisms underlying LRRFIP1’s functions could provide insights into the development of novel strategies for modulating immune responses and treating cancer. Therefore, the production and characterization of LRRFIP1 recombinant protein are pivotal in advancing our knowledge of its biological roles and developing potential therapeutic applications.
