Analytical Data
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基因名
DKK2
- Application
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别名
DKK2;Dickkopf-related Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBU2
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表达区间
26-259aa
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氨基酸序列
SQIGSSRAKL NSIKSSLGGE TPGQAANRSA GMYQGLAFGG SKKGKNLGQA YPCSSDKECE VGRYCHSPHQ GSSACMVCRR KKKRCHRDGM CCPSTRCNNG ICIPVTESIL TPHIPALDGT RHRDRNHGHY SNHDLGWQNL GRPHTKMSHI KGHEGDPCLR SSDCIEGFCC ARHFWTKICK PVLHQGEVCT KQRKKGSHGL EIFQRCDCAK GLSCKVWKDA TYSSKARLHV CQKI
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DKK2 (Dickkopf-related protein 2) is a member of the Dickkopf family, which plays a crucial role in the regulation of the Wnt signaling pathway, a key pathway involved in developmental processes and cellular functions. Abnormal regulation of Wnt signaling is associated with various diseases, including cancer and degenerative disorders. Research into DKK2 has garnered interest due to its differential expression in various tissues and its potential role as a biomarker and therapeutic target. Recombination studies of DKK2 protein have facilitated the exploration of its structure, function, and interactions with other molecules, leading to a better understanding of its role in cellular signaling and its impact on tumorigenesis and tissue homeostasis. Additionally, the generation of recombinant DKK2 proteins allows for the development of specific inhibitors or agonists that could modulate Wnt signaling for therapeutic purposes. With the increasing evidence of DKK2’s involvement in pathological conditions, understanding its mechanisms and effects at the molecular level holds promise for novel therapeutic strategies in treating diseases where Wnt signaling is dysregulated.












