Analytical Data
-
基因名
DIMT1
- Application
-
别名
DIMT1；DIMT1L;Probable dimethyladenosine transferase
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UNQ2
-
表达区间
1-313aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MMPKVKSGAI GRRRGRQEQR RELKSAGGLM FNTGIGQHIL KNPLIINSII DKAALRPTDV VLEVGPGTGN MTVKLLEKAK KVVACELDPR LVAELHKRVQ GTPVASKLQV LVGDVLKTDL PFFDTCVANL PYQISSPFVF KLLLHRPFFR CAILMFQREF ALRLVAKPGD KLYCRLSINT QLLARVDHLM KVGKNNFRPP PKVESSVVRI EPKNPPPPIN FQEWDGLVRI TFVRKNKTLS AAFKSSAVQQ LLEKNYRIHC SVHNIIIPED FSIADKIQQI LTSTGFSDKR ARSMDIDDFI RLLHGFNAEG IHFS
-
分子量
38 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DIMT1 (Dosage-Independent Modifier of Tail), a protein associated with gene expression regulation, is particularly significant in the study of developmental biology and genetic disorders. Research has shown that DIMT1 plays a crucial role in modulating the expression of various genes during embryonic development, possibly influencing traits such as limb formation and organ development. The protein is known to interact with multiple transcription factors and chromatin remodeling complexes, highlighting its importance in the epigenetic control of gene activity. Understanding DIMT1's function could provide insight into its potential implications in congenital conditions and cancer, where gene expression goes awry. The recombinant production of DIMT1 allows for detailed functional studies, providing a platform to explore its interactions and mechanisms at a molecular level. This research is pivotal in deciphering the complex regulatory networks governing development and disease. By elucidating the role of DIMT1, scientists aim to uncover not only the basic biological processes but also its potential as a target for therapeutic intervention in conditions linked to its dysregulation.
